Purpose:
One mission of the NIH-funded Kansas IDeA Network of Biomedical Research Excellence (Kansas INBRE) grant is to strengthen the critical mass of junior investigators at K-INBRE network campuses through the administration of the Developmental Research Project Program (DRPP). The DRPP Award is designed to support young investigators to aid them in building their research programs.
Letter of Intent:
Submit a letter of intent through REDCap by noon on November 1, 2024 (or the next business day if the deadline falls on a weekend or a holiday). Your one-page letter of intent should summarize a 2-year NIH-related biomedical research plan that could be accomplished with a $75,000/year budget. Identify your proposed mentor's name and institution and briefly comment on the points listed under the criteria. Please use the "SAVE AND RETURN" feature in REDCap once your letter of intent is uploaded. The system will maintain your information until you are ready to submit your complete proposal submission by December 1, (or the next business day, if the deadline falls on a weekend or a holiday). The criteria for selection of outstanding research proposals are as follows:
Criteria:
* Appropriate NIH-related scientific focus
* Strong and exciting hypothesis with well-developed rationale.
* Minimum requirement for extensive preliminary data.
* Junior Investigator within 5 years of hiring (both tenure track and research track faculty are eligible) at one of the K-INBRE network institutions
* An experienced mentor identified (preferably at the same institution) with a strong history of NIH funding. If no institutional mentor is available or appropriate, outside mentors are acceptable but must be at a university in Kansas. Mentoring teams of one or more mentors may also be appropriate.
* The applicant's institution must guarantee to provide 6 calendar months of release time to perform the research. Junior investigators must devote at least 50% of their professional effort to research, including career development. Thus, no more than 50% time should be committed to teaching or administrative duties.
* The INBRE application must represent a new, unfunded project at the time of submission.
* Investigators who have received a research grant with direct costs of more than $50,000/year from NIH (including COBRE and INBRE grants) or another extramural funding agency are not eligible to apply.
* K-INBRE Developmental Research Project Program awardees may not concurrently hold a COBRE grant.
Proposal Format:
The following pages can be downloaded from this site: http://grants.nih.gov/grants/funding/phs398/phs398.html
* Form Page 1: Face Page (with signature from appropriate institutional official)
* Form Page 2: Summary, Relevance, Project/Performance Sites, Senior/key Personnel, Other Significant Contributors, and Human Embryonic Stem Cells
* Form Page 3: Research Grant Table of Contents
* Form Page 4: Detailed Budget for Initial Budget Period
* Form Page 5: Budget for Entire Proposed Project Period (Include justification)
SF424 budgets OR Excel Spreadsheets will be accepted in place of the PHS398 budget sheets. Please reach out to us if you would like a template. Please also include a budget justification. See the template here: Detailed Budget Justification Template.docx
* Biographical Sketch Format Page (Include a biographical sketch for the applicant and the mentor)
* Resources Format Page
* Checklist Form Page
* Continuation Format Page
* Letter from department chair guaranteeing release time to perform research. 50% effort must be committed to the research activities.
* A letter of commitment and mentoring plan from the mentor should follow that includes a discussion of the mentoring relationship, frequency of meetings, and plans for career development.
Use an Arial typeface, a black font color, and a font size of 11 points or larger. The research plan should not exceed 6 pages and should include:
* Specific Aims
* Research Strategy (Significance, Innovation, Approach, Expected Outcomes, Statistics and Rigor, Mentoring Plan, Alternative Strategies, Timeline)
The following should be addressed but are not included within the 6-page limit:
* Bibliography and References Cited
* Vertebrate Animals
* Select Agent Research
* Consortium/Contractual Arrangements
* Letters of Support
* Resource Sharing Plan(s)
* Authentication of Key Biological and/or Chemical Resources
*PHS Human Subjects and Clinical Trials Information
* Appendices may not be included
Peer Review:
Proposals will be reviewed by external reviewers, the K-INBRE Incentives and Awards Committee and the K-INBRE External Advisory Committee, with the major criteria being the importance and strength of the science and the likelihood of developing successfully into an NIH-funded project. Once approved by these committees, the proposal will be submitted to NIGMS for administrative review.
Funding:
Grants are awarded for 2 years assuming that progress is acceptable to the review committee. The grant award is for $150,000 (direct costs), and the budget should not exceed $75,000 (direct costs) during either year. F&A will be in addition to the $150,000 and should be calculated as appropriate to your campus for Facilities & Administrative Cost (F&A) recovery. Remember, an investigator must commit 6 calendar months effort to the project.
All awards are contingent on project approval from NIGMS and the availability of future funds from NIH.
Submission:
All proposals must be submitted through REDCap by 12:00 noon on December 1, (or the next business day, if the deadline falls on a weekend or a holiday). Announcements of awards are planned before May 1. The earliest possible start date will be May 1, 2025. Funds will be made available upon approval from NIH and must be spent or encumbered by April 30, of the following year. Each application should be submitted through REDCap as a single PDF file.
* KUMC applicants should submit proposals directly to REDCap. After funding decisions have been made, awarded KUMC proposals will be routed through the KUMC Sponsored Programs Office for approvals and signatures.
* All other submissions should include a signature from an authorized official.
Deadlines:
Letter of Intent submitted through REDCap by noon on November 1, (or the next business day, if the deadline falls on a weekend or a holiday).
Full proposals are due December 1, by 12:00 noon (or the next business day, if the deadline falls on a weekend or a holiday).
Evaluation:
Quarterly progress reports are required to satisfy NIH's new Uniform Guidance policy. These reports will also be provided to the Developmental Research Project Program oversight committee. An NIH grant submission (R01, R21, R16, R15) is encouraged by the end of this 2-year award.
Acknowledgement:
When K-INBRE funds have supported your research, please remember to acknowledge this support by including the grant number P20GM103418, regardless of the time period between receipt of funding and the publication or presentation.
Further Information:
Call or e-mail Heiata J. Chapman, Executive Director, K-INBRE, (913) 588-7170, hchapman@kumc.edu
Funding Expectations:
Acknowledgement: When K-INBRE funds have supported your research, please remember to cite this support by including the grant number P20 GM103418, regardless of the time period between receipt of funding and the publication or presentation.
Mentoring: The Awardee and Mentor will follow their submitted mentoring plan.
Progress Reports: Provide periodic reports to satisfy NIH/sponsor requests/requirements.
Resubmission: Resubmit your grant within the time frame listed on your application.
K-INBRE Annual Symposium: Please plan to attend the annual K-INBRE symposium in January which is held on Martin Luther King Jr. weekend each year.